PRF (Platelet-Rich Fibrin) Skin Rejuvenation in Sherman Oaks
Refresh your skin with the power of your body’s own healing. At GC Skin Medspa in Sherman Oaks, Dr. Luciana Yacomotti, M.D. offers Platelet-Rich Fibrin (PRF)—an advanced, all-natural treatment that encourages collagen renewal, improves texture, and restores youthful radiance.collagen renewal, improves texture, and restores youthful
What Is PRF & How Does It Work?
Natural Healing Therapy
Derived from your blood via gentle centrifugation (no additives), PRF contains a three-dimensional fibrin matrix packed with platelets, growth factors, and immune cells that promote sustained skin healing.
Sustained Growth Factor Release
Unlike fast-releasing PRP, PRF provides a slower, longer-lasting release of bioactive substances—stimulating collagen, elastin, stem cell activity, and tissue remodeling over time.
What Is PRF & How Does It Work?
Stimulates Collagen & Elastin Production — Rejuvenates skin structure and firmness.
Improves Texture, Tone & Fine Lines — Reduces signs of aging for a smoother, radiant complexion.
Safe, Autologous Treatment — Low risk of allergic reactions, using your own blood for maximum biocompatibility.
Natural Healing Promoter — Enhances tissue repair and skin quality over time.
The platelet-rich fibrin treatment has been proven to be superior and more efficient than PRP due to its capacity to release the growth factors over time, encouraging longer-term benefits than the platelet-rich plasma procedure.
Schedule a
Consultation
Treatment Process & What to Expect
Personalized Consultation
Dr. Yacomotti assesses your skin goals and designs your PRF treatment plan.
Procedure Steps
Blood is drawn from you, processed to isolate PRF, and then applied via topical or microneedling techniques—usually completed in ~30 minutes.
Recovery & Side Effects
Expect mild redness or swelling for 1–3 days—mostly manageable. Subsequent collagen remodeling supports long-term improvement.
Who Is a Great Candidate?
Ideal for those wanting to:
- Smooth fine lines and improve skin texture
- Treat under-eye darkness, nasolabial folds, or acne scars
- Enhance facial glow without chemicals or major downtime
Suitable for most healthy adults
Note: Not recommended for individuals with active infection or certain medical conditions—consultation ensures safe candidacy
Pre- & Post-Treatment Care Tips
Before: Avoid retinoids, exfoliation, and sun for several days.
After: Keep skin hydrated, avoid strong skincare for 24 hours, and use SPF. Mild redness and sensitivity may occur.
Frequently Asked Questions
Most find it mild—some describe a slight microneedling sensation if applicable—but numbing can be used.
Many clients benefit from 3–4 sessions, spaced monthly, with maintenance every 6–12 months.
You may see subtle glow immediately, with improved texture and firmness unfolding over a few weeks as collagen rebuilds.
Minimal—since it’s your own blood, allergic responses are rare. Temporary redness or bruising is normal.
PRF - Platelet rich fibrin
Platelet-Rich Fibrin (PRF) is an all-natural solution that can treat areas in the face that show the first signs of aging, like under-eye hollows, deflated cheeks and in the scalp for hair restoration. It is the most innovative and advanced non-surgical facial and hair restoration treatment.
It uses your body’s own stem cells to stimulate collagen production, tissue regeneration, and hair regrowth. Since PRF growth factors come from your own blood, the body more easily accepts the treatment and increases natural tissue regeneration
Face
PRF helps your face by improving your overall skin tone and texture, resulting in a more youthful and natural looking appearance.
Scalp
PRF helps your scalp by stimulating hair follicles, making them larger and healthier so they can produce thicker hair. Whether you’re a man or woman, you will see benefits such as the reduction of thinning hair, a receding hairline and baldness (including small bald spots).
Ready for Natural Radiance? Book Your PRF Appointment
Elevate skin quality with PRF at GC Skin Medspa, guided by Dr. Luciana Yacomotti, M.D.
Location: 13320 Riverside Dr, Suite 218, Sherman Oaks, CA 91423
Call: (818) 458-9556
How long PRF (platelet-rich-fibrin) last?
Who can get PRF treatments
